Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

Base Information

Chemical Name:Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
CAS No.:179688-26-7
Molecular Formula:C15H21NO8
Molecular Weight:343.334
Hs Code.:2918990090
European Community (EC) Number:605-866-9
DSSTox Substance ID:DTXSID30458151
Wikidata:Q72473034
Mol file:179688-26-7.mol

Synonyms:Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;179688-26-7;ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;Benzoic acid, 4,5-bis(2-methoxyethoxy)-2-nitro-, ethyl ester;MFCD06797662;EC 605-866-9;Ethyl 4,5-bis(2-methoxyethoxy)-2-nitro-benzoate;4,5-bis(2-methoxyethoxy)-2-nitrobenzoic acid ethyl ester;SCHEMBL264575;DTXSID30458151;VOHOFZNVWZWVMA-UHFFFAOYSA-N;AMY19331;BCP02603;AKOS015888609;AC-8520;FD16017;AS-11437;SY111438;FT-0656275;A812476;ethyl 4,5-bis-(2-methoxy-ethoxy)-2-nitro-benzoate;2-nitro-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester

Suppliers and Price of Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate
250mg
$ 65.00

Matrix Scientific
Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 95+%
1g
$ 103.00

Matrix Scientific
Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 95+%
5g
$ 357.00

Crysdot
Ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 97%
1g
$ 80.00

Crysdot
Ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 97%
10g
$ 420.00

Crysdot
Ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 97%
5g
$ 240.00

Chemenu
Ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 95+%
5g
$ 224.00

Chemenu
Ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 95+%
10g
$ 393.00

AvaChem
Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
10g
$ 445.00

AvaChem
Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
100mg
$ 45.00

Total 64 raw suppliers

Chemical Property of Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

Chemical Property:

Vapor Pressure:6.29E-09mmHg at 25°C
Refractive Index:1.51
Boiling Point:467.8 °C at 760 mmHg
Flash Point:185.6 °C
PSA：109.04000
Density:1.215 g/cm³
LogP:2.34510
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Ethyl Acetate (Slightly)
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:11
Exact Mass:343.12671663
Heavy Atom Count:24
Complexity:386

Purity/Quality:

99% ^*data from raw suppliers

Ethyl4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=C(C=C1[N+](=O)[O-])OCCOC)OCCOC
Uses Ethyl 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate is used in the syntheses of 4-(indol-3-yl)quinazolines as epidermal growth factor receptor tyrosine kinase inhibitors. It is also used to prepare Erlotinib hydrochloride (E625000), a useful drug in treatment of non-?small-?cell lung cancer.

Technology Process of Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

There total 9 articles about Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%