3-(2-Fluorophenyl)-3-hydroxypropanoic acid

Base Information

Chemical Name:3-(2-Fluorophenyl)-3-hydroxypropanoic acid
CAS No.:60187-07-7
Molecular Formula:C₉H₉FO₃
Molecular Weight:184.167
Hs Code.:
DSSTox Substance ID:DTXSID901280200

Synonyms:3-(2-fluorophenyl)-3-hydroxypropanoic acid;60187-07-7;Benzenepropanoic acid, 2-fluoro-beta-hydroxy-;SCHEMBL8770868;DTXSID901280200;MFCD16302335;AKOS011683198;2-Fluoro-I(2)-hydroxybenzenepropanoic acid;CS-0345578;EN300-1841870

Suppliers and Price of 3-(2-Fluorophenyl)-3-hydroxypropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-(2-Fluorophenyl)-3-hydroxypropanoic acid

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:184.05357231
Heavy Atom Count:13
Complexity:184

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(CC(=O)O)O)F

Technology Process of 3-(2-Fluorophenyl)-3-hydroxypropanoic acid

There total 3 articles about 3-(2-Fluorophenyl)-3-hydroxypropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 70200-11-2,550363-92-3
ethyl 3-(2-fluorophenyl)-3-hydroxypropionate

: 60187-07-7
3-hydroxy-3-(2-fluorophenyl)propanoic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; at 20 ℃; for 3h;
DOI:10.1039/c5ob01380a

Reference yield:

: 446-52-6
2-Fluorobenzaldehyde

: 60187-07-7
3-hydroxy-3-(2-fluorophenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / N,N-dimethyl-formamide / 20 h / 80 °C

2: sodium hydroxide; water / ethanol / 3 h / 20 °C

With water; triethylamine; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1039/c5ob01380a