2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole

Base Information

Chemical Name:2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole
CAS No.:1458715-41-7
Molecular Formula:C₂₄H₁₇FN₂S
Molecular Weight:384.477
Hs Code.:

Synonyms:2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole

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Chemical Property of 2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole

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Technology Process of 2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole

There total 7 articles about 2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 6278-73-5
2-(4-aminophenyl)benzothiazole

: 123183-95-9
1-(4-fluoro-phenyl)-pentane-1,4-dione

: 1458715-41-7
2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole

Guidance literature:: With potassium hydrogensulfate; In ethanol; for 1h; Reflux; Green chemistry;
DOI:10.1016/j.bmcl.2013.07.068

Reference yield:

: 6244-77-5
4-nitro-N-phenylthiobenzamide

: 1458715-41-7
2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide; potassium hexacyanoferrate(III) / water; ethanol / 3 h / 90 °C

2: tin(II) chloride dihdyrate / ethanol / 2 h / Reflux

3: potassium hydrogensulfate / ethanol / 1 h / Reflux; Green chemistry

With potassium hydrogensulfate; tin(II) chloride dihdyrate; sodium hydroxide; potassium hexacyanoferrate(III); In ethanol; water; 3: |Paal-Knorr Pyrrole Synthesis;
DOI:10.1016/j.bmcl.2013.07.068

Reference yield:

: 22868-34-4
2-(4-nitrophenyl)benzothiazole

: 1458715-41-7
2-(4-(2-(4-fluorophenyl)-5-methyl-1H-pyrrol-1-yl)phenyl)benzo[d]thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: tin(II) chloride dihdyrate / ethanol / 2 h / Reflux

2: potassium hydrogensulfate / ethanol / 1 h / Reflux; Green chemistry

With potassium hydrogensulfate; tin(II) chloride dihdyrate; In ethanol; 2: |Paal-Knorr Pyrrole Synthesis;
DOI:10.1016/j.bmcl.2013.07.068