4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid

Base Information

Chemical Name:4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid
CAS No.:77716-11-1
Molecular Formula:C11H16N2O4
Molecular Weight:240.259
Hs Code.:29242990
European Community (EC) Number:673-963-3
DSSTox Substance ID:DTXSID10370847
Nikkaji Number:J1.367.777H
Wikidata:Q72509888
Mol file:77716-11-1.mol

Synonyms:77716-11-1;4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid;4-tert-Butoxycarbonylamino-1-methyl-1H-pyrrole-2-carboxylic acid;4-(boc-amino)-1-methyl-1h-pyrrole-2-carboxylic acid;4-[(tert-butoxycarbonyl)amino]-1-methyl-1h-pyrrole-2-carboxylic acid;1-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]pyrrole-2-carboxylic acid;4-(tert-butoxycarbonylamino)-1-methyl-1H-pyrrole-2-carboxylic acid;4-(Boc-amino)-1-methylpyrrole-2-carboxylic acid;MFCD02094544;4-{[(tert-butoxy)carbonyl]amino}-1-methyl-1H-pyrrole-2-carboxylic acid;Maybridge1_008798;Oprea1_532277;BOC-4-AMINO-1-METHYLPYRROLE-2-CARBOXYLIC ACID;SCHEMBL1845748;HMS566H20;DTXSID10370847;GOLAEMFBWAIGRX-UHFFFAOYSA-N;BOC-NH(4)-MEPYL(2)-OH;4-[(tert-butoxycarbonyl)amino]-1-methylpyrrole-2-carboxylic acid;4-tert-butoxycarbonylamino-1-methyl-1H-pyrrole-2carboxylicacid;AMY36582;4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylicacid;CCG-52621;AKOS015850634;AC-8259;CS-W012807;SY026150;TS-00713;A9820;FT-0617323;W10740;EN300-6496114;1-methyl-4-(BOC amino)pyrrole-2-carboxylic acid;4-Boc-Amino-1-methyl-1H-pyrrole-2-carboxylic acid;J-515998;SR-01000641841-1;BRD-K37450091-001-01-7;Z1505694027;4-[(t-butoxycarbonyl)amino]-1-methylpyrrole-2-carboxylic acid;1-Methyl-4-(tert-butoxycarbonylamino)-1H-pyrrole-2-carboxylic acid;4-(Boc-amino)-1-methylpyrrole-2-carboxylic acid, >=99.0% (HPLC);4-[(tert-Butoxycarbonyl)amino]-1-methylpyrrole-2carboxylic acid;4-[[(tert-Butyloxy)carbonyl]- amino]-1-methylpyrrole-2-carboxylic acid;4-[[(tert-Butyloxy)carbonyl]-amino]-1-methylpyrrole-2-carboxylic acid;4-(tert-butoxycarbonyl)-1-methyl-1H-pyrrole-2-carboxylic acid

Suppliers and Price of 4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Boc-amino)-1-methylpyrrole-2-carboxylic acid
250mg
$ 70.00

SynQuest Laboratories
4-Amino-1-methyl-1H-pyrrole-2-carboxylic acid, 4-Boc protected 97%
1 g
$ 75.00

SynQuest Laboratories
4-Amino-1-methyl-1H-pyrrole-2-carboxylic acid, 4-Boc protected 97%
5 g
$ 145.00

Sigma-Aldrich
4-(Boc-amino)-1-methylpyrrole-2-carboxylic acid ≥99.0% (HPLC)
1g
$ 298.00

Medical Isotopes, Inc.
4-(Boc-amino)-1-methyl-1H-pyrrole-2-carboxylicacid
1 g
$ 465.00

Frontier Specialty Chemicals
Boc-4-amino-1-methylpyrrole-2-carboxylicacid 98%
1g
$ 476.00

Crysdot
4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylicacid 95+%
25g
$ 634.00

Crysdot
4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylicacid 95+%
5g
$ 228.00

Crysdot
4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylicacid 95+%
10g
$ 401.00

Crysdot
4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylicacid 95+%
1g
$ 94.00

Total 35 raw suppliers

Chemical Property of 4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid

Chemical Property:

Vapor Pressure:1.18E-05mmHg at 25°C
Melting Point:156-160 °C (dec.)
Refractive Index:1.536
Boiling Point:355 °C at 760 mmHg
PKA:4.66±0.41(Predicted)
Flash Point:168.5 °C
PSA：80.56000
Density:1.21 g/cm³
LogP:1.75320
Storage Temp.:-15°C
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:240.11100700
Heavy Atom Count:17
Complexity:311

Purity/Quality:

97% ^*data from raw suppliers

4-(Boc-amino)-1-methylpyrrole-2-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CN(C(=C1)C(=O)O)C
Uses 4-(Boc-amino)-1-methylpyrrole-2-carboxylic Acid is an unnatural amino acid for preparing heteroaromatic oligoamides for regulating gen expression in biotechnology.

Technology Process of 4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid

There total 17 articles about 4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 126092-96-4
methyl 4-<<(tert-butyloxy)carbonyl>amino>-1-methyl-pyrrole-2-carboxylate

: 77716-11-1
4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; methanol; at 60 ℃; for 9h;
DOI:10.1021/jo048686r

Reference yield: 93.0%

: 77716-11-1
4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid

Guidance literature:

Reference yield: 89.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 13138-76-6
1-methyl-4-nitropyrrole-2-carboxylic acid methyl ester

: 77716-11-1
4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid

Guidance literature:: 1-methyl-4-nitropyrrole-2-carboxylic acid methyl ester; With hydrogen; palladium 10% on activated carbon; In ethyl acetate; at 20 ℃; for 12h;

di-tert-butyl dicarbonate; In diethyl ether; at 20 ℃; for 2h;

With sodium hydroxide; In methanol; water; at 60 ℃; for 2h;