2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone

Base Information

• Chemical Name: 2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone
• CAS No.: 40364-94-1
• Molecular Formula: C₁₁H₁₄N₄O₆
• Molecular Weight: 298.255
• Mol file: 40364-94-1.mol

Synonyms:2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone

Chemical Property of 2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone

There total 4 articles about 2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxy-2-(hydroxymethyl)-2-methylpropanal (18516-18-2) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone (40364-94-1)

Guidance literature:

With phosphoric acid; In ethanol; at 55 ℃; for 2h;

DOI:10.1021/ac980699f

Reference yield:

diethoxymethyl-methyl-malonic acid diethyl ester (40364-91-8) → 2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone (40364-94-1)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: AcOH / bis-(2-methoxy-ethyl) ether

With lithium aluminium tetrahydride; acetic acid; In diethyl ether; diethylene glycol dimethyl ether;

Reference yield:

2-diethoxymethyl-2-methyl-propane-1,3-diol (40364-92-9) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 2,2-bis(hydroxymethyl)propionaldehyde 2,4-dinitrophenylhydrazone (40364-94-1)

Guidance literature:

With acetic acid; In diethylene glycol dimethyl ether;

upstream raw materials:

2-diethoxymethyl-2-methyl-propane-1,3-diol

(2,4-dinitro-phenyl)-hydrazine

3-hydroxy-2-(hydroxymethyl)-2-methylpropanal

diethoxymethyl-methyl-malonic acid diethyl ester