5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide

Base Information

Chemical Name:5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide
CAS No.:1452520-62-5
Molecular Formula:C₂₄H₃₆N₄O₂
Molecular Weight:412.575
Hs Code.:

Synonyms:5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide

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Chemical Property of 5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide

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Technology Process of 5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide

There total 6 articles about 5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 5-methoxy-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamide hydrochloride

: 22565-20-4
1-(2-bromoethyl)-3-methylcyclohexane

: 1452520-62-5
5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide

Guidance literature:: 5-methoxy-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamide hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 1h;

1-(2-bromoethyl)-3-methylcyclohexane; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield: 18.0%

: 1452520-78-3
5-bromo-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamide hydrochloride

: 22565-20-4
1-(2-bromoethyl)-3-methylcyclohexane

: 1452520-62-5
5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide

Guidance literature:: 5-bromo-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamide hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 1h;

1-(2-bromoethyl)-3-methylcyclohexane; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield: 18.0%

: 1452520-74-9
5-methoxy-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamide hydrochloride

: 22565-20-4
1-(2-bromoethyl)-3-methylcyclohexane

: 1452520-62-5
5-methoxy-N-({1-[2-(3-methyl cyclohexyl)ethyl]piperidin-4-yl}methyl)-1H-indazole-3-carboxamide

Guidance literature:: 5-methoxy-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamide hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 1h;

1-(2-bromoethyl)-3-methylcyclohexane; In N,N-dimethyl-formamide; at 80 ℃;
DOI:10.1021/acs.jmedchem.5b01208