1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

Base Information

Chemical Name:1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide
CAS No.:151130-78-8
Molecular Formula:C₃₀H₃₄N₂O₃
Molecular Weight:470.612
Hs Code.:

Synonyms:1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

Suppliers and Price of 1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

There total 7 articles about 1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21384-53-2,31907-91-2,196965-62-5
methyl 1-benzylaziridine-2-carboxylate

: 151130-78-8
1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) potassium trimethylsilanolate / 1.) THF, room temp., 2 h, 2.) CH₂Cl₂, 0 deg C

2: DMAP / CH₂Cl₂ / Ambient temperature

With dmap; potassium trimethylsilonate; In dichloromethane;
DOI:10.1021/jo00070a035

Reference yield:

: 88730-60-3
(Z)-6-(tetrahydro-2H-pyran-2-yloxy)hex-3-en-1-ol

: 151130-78-8
1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / Ph₃P, diisopropyl azodicarboxylate / tetrahydrofuran / 24 h

2: 82 percent / TsOH / methanol / 1 h / Ambient temperature

3: 93 percent / Et₃N / CH₂Cl₂ / 3 h / Ambient temperature

4: 83 percent / Et₃N / 1,2-dimethoxy-ethane / Heating

5: DMAP / CH₂Cl₂ / Ambient temperature

With dmap; di-isopropyl azodicarboxylate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1021/jo00070a035

Reference yield:

: 150-76-5
4-methoxy-phenol

: 151130-78-8
1-Benzyl-aziridine-2-carboxylic acid benzyl-[(Z)-6-(4-methoxy-phenoxy)-hex-3-enyl]-amide

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / Ph₃P, diisopropyl azodicarboxylate / tetrahydrofuran / 24 h

2: 82 percent / TsOH / methanol / 1 h / Ambient temperature

3: 93 percent / Et₃N / CH₂Cl₂ / 3 h / Ambient temperature

4: 83 percent / Et₃N / 1,2-dimethoxy-ethane / Heating

5: DMAP / CH₂Cl₂ / Ambient temperature

With dmap; di-isopropyl azodicarboxylate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1021/jo00070a035