2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide

Base Information

• Chemical Name: 2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide
• CAS No.: 1253186-56-9
• Molecular Formula: C₁₈H₁₂F₅N₃O₂
• Molecular Weight: 397.304

Synonyms:2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide

Chemical Property of 2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide

Chemical Property:

• Boiling Point: 462.2±45.0 °C(Predicted)
• Density: 1.46±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

GSK-7975A 99.79% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide

There total 1 articles about 2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-difluoro-N-(1-{[4-(methyloxy)-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide (1253186-61-6) → 2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide (1253186-56-9)

Guidance literature:

With boron tribromide; In dichloromethane; at 20 ℃; for 18h; Inert atmosphere;

Reference yield:

2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide (1253186-56-9) → 2,6-difluoro-N-(1-{[4-hydroxy-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide sodium salt (1253187-70-0)

Guidance literature:

With sodium hydroxide; In water; at 60 ℃; for 5h;

Reference yield:

2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide (1253186-56-9) + 2-Bromoethyl methyl ether (6482-24-2) → 2,6-difluoro-N-(1-{[4-{[2-(methyloxy)ethyl]oxy}-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide (1253186-64-9)

Guidance literature:

With caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 6h; Inert atmosphere;

upstream raw materials:

2,6-difluoro-N-(1-{[4-(methyloxy)-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide

Downstream raw materials:

2,6-difluoro-N-(1-{[4-{[2-(methyloxy)ethyl]oxy}-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide

2,6-difluoro-N-(1-{[4-[(4-pyridinylmethyl)oxy]-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide trifluoroacetate

2,6-difluoro-N-(1-{[4-[(3-pyridinylmethyl)oxy]-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide trifluoroacetate

2,6-difluoro-N-(1-{[4-(methyloxy)-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1253186-56-9 2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send