4-Methylphenyl boronic acid anhydride

Base Information

• Chemical Name: 4-Methylphenyl boronic acid anhydride
• CAS No.: 5084-80-0
• Molecular Formula: C21H21B3O3
• Molecular Weight: 353.829
• Hs Code.: 2934999090
• Mol file: 5084-80-0.mol

Synonyms:Boroxin,tri-p-tolyl- (6CI,7CI,8CI);2,4,6-Tri-p-tolylcyclotrioxaborane;Tri(p-tolyl)boroxine;Tris(4-Methylphenyl)boroxin;Tris(4-tolyl)boroxin;

Chemical Property of 4-Methylphenyl boronic acid anhydride

Chemical Property:

• Vapor Pressure: 1.6E-06mmHg at 25°C
• Refractive Index: 1.555
• Boiling Point: 408.9 °C at 760 mmHg
• Flash Point: 201.1 °C
• PSA: 27.69000
• Density: 1.09 g/cm³
• LogP: 2.16120

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Methylphenyl boronic acid anhydride

There total 13 articles about 4-Methylphenyl boronic acid anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-methylphenylboronic acid (5720-05-8) → tri(4-tolyl)boroxine (5084-80-0)

Guidance literature:

In toluene; at 120 ℃; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1002/anie.202011491

Reference yield: 80.0%

para-bromotoluene (106-38-7) → tri(4-tolyl)boroxine (5084-80-0)

Guidance literature:

para-bromotoluene; With iodine; magnesium; ethylene dibromide; In tetrahydrofuran; for 1h; Heating;

With Trimethyl borate; In tetrahydrofuran; at -78 ℃; for 2h;

DOI:10.1055/s-2006-926234

Reference yield: 75.0%

Trimethyl borate (121-43-7,63156-11-6) → tri(4-tolyl)boroxine (5084-80-0)

Guidance literature:

para-bromotoluene; With iodine; magnesium; ethylene dibromide; In tetrahydrofuran; for 2h; Heating / reflux;

Trimethyl borate; In tetrahydrofuran; at -78 ℃; for 2h;

With water; In tetrahydrofuran;

upstream raw materials:

4-methylphenylboronic acid

para-bromotoluene

4-(bromo(ethoxy)boryl)toluene

4-(dibromoboryl)toluene

Downstream raw materials:

dichloro-p-tolyl-borane

tris(4-bromomethyl phenyl)boroxine

tris(4-dibromomethyl phenyl)boroxine

2-p-tolyl-[1,3,6,2]dioxazaborocane