Bz(4-OMe)-Z-ΔAbu-OMe

Base Information

• Chemical Name: Bz(4-OMe)-Z-ΔAbu-OMe
• CAS No.: 1084940-98-6
• Molecular Formula: C₁₃H₁₅NO₄
• Molecular Weight: 249.266
• Mol file: 1084940-98-6.mol

Synonyms:Bz(4-OMe)-Z-ΔAbu-OMe

Chemical Property of Bz(4-OMe)-Z-ΔAbu-OMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bz(4-OMe)-Z-ΔAbu-OMe

There total 1 articles about Bz(4-OMe)-Z-ΔAbu-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(2S,3R)-3-hydroxy-2-(4-methoxybenzamido)-butyric acid methyl ester (704910-28-1) → Bz(4-OMe)-Z-ΔAbu-OMe (1084940-98-6)

Guidance literature:

(2S,3R)-3-hydroxy-2-(4-methoxybenzamido)-butyric acid methyl ester; With dmap; di-tert-butyl dicarbonate; In acetonitrile; at 20 ℃;

With N,N,N',N'-tetramethylguanidine; In acetonitrile; at 20 ℃; stereoselective reaction;

DOI:10.1002/ejoc.200800602

Reference yield: 73.0%

Bz(4-OMe)-Z-ΔAbu-OMe (1084940-98-6) → methyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate (1084941-03-6)

Guidance literature:

Bz(4-OMe)-Z-ΔAbu-OMe; With iodine; potassium carbonate; In tetrahydrofuran; at 80 ℃; for 3h;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 80 ℃; for 3h;

DOI:10.1002/ejoc.200800602

Reference yield:

Bz(4-OMe)-Z-ΔAbu-OMe (1084940-98-6) → Bz(4-OMe)-Z-ΔAbu(β-Br)-OMe (1242683-10-8) + Bz(4-OMe)-E-ΔAbu(β-Br)-OMe (1242683-08-4)

Guidance literature:

Bz(4-OMe)-Z-ΔAbu-OMe; With N-Bromosuccinimide; In dichloromethane; for 16h;

With triethylamine; In dichloromethane; for 1h;

DOI:10.1007/s00726-009-0466-x

upstream raw materials:

(2S,3R)-3-hydroxy-2-(4-methoxybenzamido)-butyric acid methyl ester

Downstream raw materials:

methyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate

Bz(4-OMe)-Z-ΔAbu(β-Br)-OMe

Bz(4-OMe)-E-ΔAbu(β-Br)-OMe

Bz(4-OMe)-Z-ΔAbu(β-I)-OMe