4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

Base Information

Chemical Name:4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone
CAS No.:935263-70-0
Molecular Formula:C₃₁H₄₈O₄Si
Molecular Weight:512.805
Hs Code.:

Synonyms:4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

Suppliers and Price of 4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

There total 4 articles about 4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 935263-62-0
4-allyl-2-hydroxy-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

: 824-94-2
p-methoxybenzyl chloride

: 935263-70-0
4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

Guidance literature:: 4-allyl-2-hydroxy-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone; With tetra-(n-butyl)ammonium iodide; caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.416667h; Inert atmosphere;

p-methoxybenzyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 2.5h; Inert atmosphere;
DOI:10.1002/chem.200903356

Reference yield:

: 80522-42-5
triisopropylsilyl trifluoromethanesulfonate

: 935263-70-0
4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

Guidance literature:: Multi-step reaction with 4 steps

1.1: (R,R)-N-[2-(2-PPh₂-benzoylamino)cyclohexyl]-2-PPh₂-benzamide; Bu₄NCl / Pd₂dba3*CHCl₃ / CH₂Cl₂ / -78 - 20 °C

1.2: 2,6-lutidine / CH₂Cl₂ / 16 h / -78 - 20 °C

2.1: CHCl₃ / 0.5 h / 100 - 120 °C / microwave irradiation

2.2: Cs₂CO₃ / Pd(OAc)2 / acetonitrile / 0.5 h / 20 °C

3.1: MgBr₂*Et₂O / CH₂Cl₂ / 1 h / 20 °C

4.1: 79 percent / Cs₂CO₃; Bu₄NI / dimethylformamide / 2.5 h / 20 °C

With tetrabutyl-ammonium chloride; tetra-(n-butyl)ammonium iodide; caesium carbonate; (1R,2R)-1,2-bis[(2-diphenylphosphanyl)benzoylamino]cyclohexane; magnesium bromide; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In dichloromethane; chloroform; N,N-dimethyl-formamide; 2.1: Claisen rearrangement / 2.2: Saegusa oxidation;
DOI:10.1021/ja070571s

Reference yield:

: 935263-61-9
5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-3-ene-1,2-dione

: 935263-70-0
4-allyl-2-(4-methoxy-benzyloxy)-5-methyl-5-(3-methyl-4-triisopropylsilanyloxy-but-2-enyl)-cyclopent-2-enone

Guidance literature:: Multi-step reaction with 2 steps

1: MgBr₂*Et₂O / CH₂Cl₂ / 1 h / 20 °C

2: 79 percent / Cs₂CO₃; Bu₄NI / dimethylformamide / 2.5 h / 20 °C

With tetra-(n-butyl)ammonium iodide; caesium carbonate; magnesium bromide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja070571s