C₁₈H₂₂O

Base Information

• Chemical Name: C₁₈H₂₂O
• CAS No.: 1421315-20-9
• Molecular Formula: C₁₈H₂₂O
• Molecular Weight: 254.372
• Mol file: 1421315-20-9.mol

Synonyms:C₁₈H₂₂O

Chemical Property of C₁₈H₂₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₂O

There total 4 articles about C₁₈H₂₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-Dimethylbut-1-yne (917-92-0) + C12H13BrO (1343343-92-9) → C18H22O (1421315-20-9)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In dichloromethane; at 80 ℃; for 20h;

DOI:10.1016/j.tetlet.2012.12.016

Reference yield:

ortho-bromobenzaldehyde (6630-33-7) → C18H22O (1421315-20-9)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / water / 0 - 20 °C

2: sodium tetrahydroborate; tellurium; propane / -78 - 20 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(l) iodide; triethylamine / dichloromethane / 20 h / 80 °C

With tellurium; sodium tetrahydroborate; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; propane; triethylamine; sodium hydroxide; In dichloromethane; water;

DOI:10.1016/j.tetlet.2012.12.016

Reference yield:

C12H11BrO (1387581-91-0) → C18H22O (1421315-20-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate; tellurium; propane / -78 - 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(l) iodide; triethylamine / dichloromethane / 20 h / 80 °C

With tellurium; sodium tetrahydroborate; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; propane; triethylamine; In dichloromethane;

DOI:10.1016/j.tetlet.2012.12.016

upstream raw materials:

3,3-Dimethylbut-1-yne

C₁₂H₁₃BrO

C₁₂H₁₁BrO

ortho-bromobenzaldehyde

Downstream raw materials:

1-(3-cyclopropylbut-3-en-1-yl)-2-(3,3-dimethylbut-1-yn-1-yl)benzene