tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate

Base Information

Chemical Name:tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate
CAS No.:742100-51-2
Molecular Formula:C₂₁H₂₈BrNO₄
Molecular Weight:438.362
Hs Code.:

Synonyms:tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate

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Technology Process of tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate

There total 1 articles about tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 742100-50-1
[1-(4-bromo-2-formylphenyl)pyrrolidin-3-yl]methyl acetate

: 56904-86-0
tert-butyl 2-(triphenylphosphoranylidene)propionate

: 742100-51-2
tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate

Guidance literature:: In toluene; Heating / reflux;

Reference yield:

: 742100-51-2
tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate

: 313747-57-8
4-(2-butoxyethoxy)phenylboric acid

: 742100-53-4
tert-butyl (2E)-3-[4-[3-(acetoxymethyl)pyrrolidin-1-yl]-4'-(2-butoxyethoxy)-1,1'-biphenyl-3-yl]-2-methylacrylate

Guidance literature:: tert-butyl (2E)-3-[2-[3-[(acetyloxy)methyl]pyrrolidin-1-yl]-5-bromophenyl]-2-methylacrylate; 4-(2-butoxyethoxy)phenylboric acid; With potassium carbonate; In ethanol; water; toluene; for 1h;

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; for 5h; Heating / reflux;