methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate

Base Information

• Chemical Name: methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate
• CAS No.: 40235-36-7
• Molecular Formula: C₁₂H₁₄N₄O₂
• Molecular Weight: 246.269
• Mol file: 40235-36-7.mol

Synonyms:methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate

Chemical Property of methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate

There total 3 articles about methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(Z)-2-bromo-3-(4-(dimethylamino)phenyl)acrylic acid methyl ester (55420-26-3) → methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate (40235-36-7)

Guidance literature:

With sodium azide; In dimethyl sulfoxide; at 90 ℃; Inert atmosphere;

DOI:10.1039/c3ob42276c

Reference yield:

→ methyl 5-(4-(dimethylamino)phenyl)-1H-1,2,3-triazole-4-carboxylate (40235-36-7)

Guidance literature:

1-Phenylsulfonyl-2-(4-dimethylaminophenyl)-acrylsaeuremethylester, NaN3;

Reference yield:

→ 5-(4-dimethylamino-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid methyl ester (40235-36-7)

Guidance literature:

Vinylsulfonylverb.6cC/NaN3;

upstream raw materials:

(Z)-2-bromo-3-(4-(dimethylamino)phenyl)acrylic acid methyl ester