1-(1-Methyl-4-piperidinyl)piperazine

Base Information

Chemical Name:1-(1-Methyl-4-piperidinyl)piperazine
CAS No.:23995-88-2
Molecular Formula:C10H21N3
Molecular Weight:183.297
Hs Code.:29335990
European Community (EC) Number:607-300-6
DSSTox Substance ID:DTXSID80340653
Wikidata:Q72495960
Mol file:23995-88-2.mol

Synonyms:23995-88-2;1-(1-Methyl-4-piperidinyl)piperazine;1-(1-methylpiperidin-4-yl)piperazine;1-(n-methylpiperidin-4-yl)piperazine;1-(1-Methyl-piperidin-4-yl)-piperazine;Piperazine, 1-(1-methyl-4-piperidinyl)-;MFCD01075186;1-Methyl-4-piperazinopiperidine;1-(1-Methyl-4-piperidino)piperazine;SCHEMBL105570;DTXSID80340653;1-(1-methyl-4-piperidyl)piperazine;STK503368;1-(N-methyl-4-piperidyl)-piperazine;1-(1-methyl-4-piperidinyl)piperizine;4-(1-methylpiperidin-4-yl)piperazine;AKOS005171545;1-(1-methylpiperidin-4-yl)-piperazin;PS-5070;1-(1-methyl-4-piperi-dinyl)piperazine;1-(1-methyl-4-piperidinyl)-piperazine;1-(1-methyl-piperidin-4-yl)-piperazin;1-(1-methyl-piperidin-4-yl)piperazine;1-(1-methylpiperidin-4-yl)-piperazine;1-(N-Methyl-piperidin-4-yl)piperazine;1-(1-methylpiperidine-4-yl)-piperazine;Piperazine, 1-(1-methyl-4-piperidyl)-;1-(1-Methyl-4-piperidinyl)piperazine #;BB 0261088;CS-0145448;FT-0638375;EN300-1852263;1-(1-Methyl-4-piperidinyl)piperazine, >=98.0% (GC)

Suppliers and Price of 1-(1-Methyl-4-piperidinyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(1-Methylpiperidin-4-yl)piperazine
1g
$ 110.00

SynQuest Laboratories
1-(1-Methylpiperidin-4-yl)piperazine 98%
25 g
$ 468.00

SynQuest Laboratories
1-(1-Methylpiperidin-4-yl)piperazine 98%
5 g
$ 173.00

SynQuest Laboratories
1-(1-Methylpiperidin-4-yl)piperazine 98%
1 g
$ 40.00

SynChem
1-(1-METHYL-4-PIPERIDINYL)PIPERAZINE 95%
1 g
$ 35.00

Sigma-Aldrich
1-(1-Methyl-4-piperidinyl)piperazine ≥98.0% (GC)
1g-f
$ 67.50

Matrix Scientific
1-(1-Methylpiperidin-4-yl)piperazine
1g
$ 58.00

Matrix Scientific
1-(1-Methylpiperidin-4-yl)piperazine
25g
$ 1210.00

Matrix Scientific
1-(1-Methylpiperidin-4-yl)piperazine
5g
$ 195.00

CHESS?
1-(1-Methyl-piperidin-4-yl)-piperazine >98
25 g
$ 20480.00

Total 65 raw suppliers

Chemical Property of 1-(1-Methyl-4-piperidinyl)piperazine

Chemical Property:

Vapor Pressure:0.0124mmHg at 25°C
Melting Point:29-32℃
Refractive Index:n20/D 1.508
Boiling Point:260.3 °C at 760 mmHg
PKA:9.28±0.10(Predicted)
Flash Point:113.2 °C
PSA：18.51000
Density:0.992 g/cm3
LogP:0.19040
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Sensitive.:Air Sensitive
Solubility.:Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:183.173547683
Heavy Atom Count:13
Complexity:146

Purity/Quality:

99%, ^*data from raw suppliers

1-(1-Methylpiperidin-4-yl)piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): C; Xi
Hazard Codes:C,Xi
Statements: 34
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(CC1)N2CCNCC2
Uses 1-(1-Methylpiperidin-4-yl)piperazine is used in preparation of Pyrazolo Estratrienes as inhibitors of 17-HSD1.

Technology Process of 1-(1-Methyl-4-piperidinyl)piperazine

There total 4 articles about 1-(1-Methyl-4-piperidinyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.8%

: 1-benzyl-4-(1-methylpiperidin-4-yl)piperazine

: 23995-88-2
1-(1-methyl-piperidin-4-yl)-piperazine

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 2h; under 3750.38 Torr;

Reference yield:

: 1445-73-4
1-Methyl-4-piperidone

: 2759-28-6
1-phenylmethylpiperazine

: 23995-88-2
1-(1-methyl-piperidin-4-yl)-piperazine

Guidance literature:: With sodium cyanoborohydride; palladium; In methanol;

Reference yield:

: 1445-73-4
1-Methyl-4-piperidone

: 23995-88-2
1-(1-methyl-piperidin-4-yl)-piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 3 h / 20 °C

2: palladium on activated charcoal; hydrogen / methanol / 2 h / 20 °C / 3750.38 Torr

With palladium on activated charcoal; hydrogen; sodium tris(acetoxy)borohydride; acetic acid; In methanol; dichloromethane;