5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide

Base Information

Chemical Name:5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide
CAS No.:188584-23-8
Molecular Formula:C₂₁H₃₅N₃O₂S
Molecular Weight:393.594
Hs Code.:

Synonyms:5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide

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Chemical Property of 5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide

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Technology Process of 5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide

There total 1 articles about 5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 35013-72-0
biotin N-Hydroxysuccinimide ester

: 188584-11-4
undec-10-ynyl-1-amine

: 188584-23-8
5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide

Guidance literature:: In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(96)01084-8

Reference yield: 84.0%

: N-benzoyl-4-iodo-L-phenylalanine methylester

: 188584-23-8
5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide

: (S)-2-Benzoylamino-3-(4-{11-[5-((3aR,6S,6aS)-2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-undec-1-ynyl}-phenyl)-propionic acid methyl ester

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In N,N-dimethyl-formamide; Ambient temperature;
DOI:10.1016/S0040-4020(96)01085-X

Reference yield: 76.0%

: 188594-27-6
3-iodo-L-(tyrosine)-methyl ester N-benzoylamide

: 188584-23-8
5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid undec-10-ynylamide

: (S)-2-Benzoylamino-3-(4-hydroxy-3-{11-[5-((3aR,6S,6aS)-2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-undec-1-ynyl}-phenyl)-propionic acid methyl ester

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In N,N-dimethyl-formamide; Ambient temperature;
DOI:10.1016/S0040-4020(96)01085-X