AC-YVAD-AFC

Base Information

• Chemical Name: AC-YVAD-AFC
• CAS No.: 219137-85-6
• Molecular Formula: C33H36 F3 N5 O10
• Molecular Weight: 719.66
• Mol file: 219137-85-6.mol

Synonyms:N-ACETYL-TYR-VAL-ALA-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;CASPASE-1 SUBSTRATE XII, FLUOROGENIC;CASPASE 1 (ICE) SUBSTRATE 2F, FLUOROGENIC;AC-YVAD-AFC;AC-TYR-VAL-ALA-ASP-7-AMINO-4-TRIFLUOROMETHYL COUMARIN;AC-TYR-VAL-ALA-ASP-AFC;N-Acetyl-Tyr-Val-Ala-Asp-(7-amino-4-trifluoromethylcoumarin)

Chemical Property of AC-YVAD-AFC

Chemical Property:

• PSA: 233.24000
• LogP: 3.44490
• Storage Temp.: −20°C
• Solubility.: DMSO (Slightly), Methanol (Silghtly)

Purity/Quality:

99% ^*data from raw suppliers

N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Ac-YVAD-AFC is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
• Uses: N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin is a substrate whose amino acids are shown as a preferred cleavage site for Caspase-1 and 4. Useful for caspase research.

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