Chemical Property of AC-DEVD-PNA
Chemical Property:
- Appearance/Colour:white
- Boiling Point:1191.1±65.0 °C(Predicted)
- PKA:2.97±0.10(Predicted)
- PSA：303.22000
- Density:1.448±0.06 g/cm3(Predicted)
- LogP:1.12240
- Storage Temp.:−20°C
- Water Solubility.:Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml).
- Purity/Quality:
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99%, *data from raw suppliers
N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide ≥97% (HPLC), powder *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Uses
N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase. N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide is an chromogenic substrate for Caspase 3 and CCP-32. N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.
