trans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid

Base Information

Chemical Name:trans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid
CAS No.:191282-48-1
Molecular Formula:C₁₄H₂₂O₄
Molecular Weight:254.326
Hs Code.:2932190090
Nikkaji Number:J1.314.059F
ChEMBL ID:CHEMBL449993
Mol file:191282-48-1.mol

Synonyms:4-methylene-2-octyl-5-oxofuran-3-carboxylic acid;C75 cpd;trans-4-carboxy-5-octyl-3-methylenebutyrolactone

Suppliers and Price of trans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid
5mg
$ 460.00

TRC
trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylicAcid
50mg
$ 1320.00

Medical Isotopes, Inc.
trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylicAcid
50 mg
$ 2200.00

DC Chemicals
C75(trans) >98%
1 g
$ 2200.00

DC Chemicals
C75(trans) >98%
250 mg
$ 1100.00

DC Chemicals
C75(trans) >98%
100 mg
$ 600.00

Crysdot
C75trans 98+%
5mg
$ 91.00

Crysdot
C75trans 98+%
50mg
$ 491.00

ChemScene
trans-C75 99.91%
50mg
$ 842.00

ChemScene
trans-C75 99.91%
10mg
$ 199.00

Total 41 raw suppliers

Chemical Property of trans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid

Chemical Property:

Appearance/Colour:White to off-white solid
Vapor Pressure:0mmHg at 25°C
Boiling Point:432.1 ºC at 760 mmHg
PKA:3.08±0.40(Predicted)
Flash Point:159.2ºC
PSA：63.60000
Density:1.08 g/cm³c
LogP:2.91940
Storage Temp.:2-8°C
Solubility.:DMSO: 18 mg/mL
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:254.15180918
Heavy Atom Count:18
Complexity:322

Purity/Quality:

99%, ^*data from raw suppliers

trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCC1C(C(=C)C(=O)O1)C(=O)O
Isomeric SMILES:CCCCCCCC[C@@H]1[C@H](C(=C)C(=O)O1)C(=O)O
Uses trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a cell cycle arrest inducer in hepatocellular carcinoma (HCC) cell lines. It has also been shown to blocks resistin-induced increases in lipid accumulation by human macrophages.

Technology Process of trans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid

There total 23 articles about trans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: (4R,5R)-4-(hydroxymethyl)-3-methylene-5-octyldihydrofuran-2(3H)-one

: 1234694-20-2,1234694-22-4,191282-49-2,191282-48-1,218137-86-1
C₇₅

Guidance literature:: With Jones reagent; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.orglett.0c04165

Reference yield: 60.0%

: 4-(hydroxymethyl)-3-methylene-5-octyldihydrofuran-2(3H)-one

: 1234694-20-2,1234694-22-4,191282-49-2,191282-48-1,218137-86-1
C₇₅

Guidance literature:: With Jones reagent; at 23 ℃; for 0.166667h; Inert atmosphere;
DOI:10.1021/acs.orglett.0c04165

Reference yield: 29.0%

: 1234694-21-3
methyl (2S,3R)-4-methylene-5-oxo-2-octyltetrahydrofuran-3-carboxylate

: 1234694-20-2,1234694-22-4,191282-49-2,191282-48-1,218137-86-1
C₇₅

Guidance literature:: With liver acetone powder equine; In aq. phosphate buffer; acetone; for 24h; pH=7.4; enantioselective reaction; Enzymatic reaction;
DOI:10.1002/chir.22419