S-naphthalen-2-yl (phenyl)phenylphosphinothioate

Base Information

• Chemical Name: S-naphthalen-2-yl (phenyl)phenylphosphinothioate
• CAS No.: 21081-96-9
• Molecular Formula: C₂₂H₁₇OPS
• Molecular Weight: 360.416
• Mol file: 21081-96-9.mol

Synonyms:S-naphthalen-2-yl (phenyl)phenylphosphinothioate

Chemical Property of S-naphthalen-2-yl (phenyl)phenylphosphinothioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-naphthalen-2-yl (phenyl)phenylphosphinothioate

There total 8 articles about S-naphthalen-2-yl (phenyl)phenylphosphinothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-Naphthalenethiol (91-60-1) + Diphenylphosphine oxide (4559-70-0) → S-naphthalen-2-yl (phenyl)phenylphosphinothioate (21081-96-9)

Guidance literature:

With trifluoromethylsulfonic anhydride; In dimethyl sulfoxide; acetonitrile; at 20 ℃; for 12h; Inert atmosphere;

Reference yield: 87.0%

Diphenylphosphine oxide (4559-70-0) + 2-Naphthalenesulfonyl chloride (93-11-8) → S-naphthalen-2-yl (phenyl)phenylphosphinothioate (21081-96-9)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1039/c6ob02364a

Reference yield: 86.0%

diphenyl-phosphinic acid (1707-03-5) + 2-Naphthalenethiol (91-60-1) → S-naphthalen-2-yl (phenyl)phenylphosphinothioate (21081-96-9)

Guidance literature:

With N,N-dimethyl-aniline; 1,1'-carbonyldiimidazole; In acetonitrile; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.tetlet.2017.05.036

upstream raw materials:

2-Naphthalenethiol

Diphenylphosphine oxide

2-Naphthalenesulfonyl chloride

diphenyl-phosphinic acid

Refernces

• 1、 Shen, Jian,Li, Qi-Wei,Zhang, Xin-Yue,Wang, Xue,Li, Gui-Zhi,Li, Wen-Zuo,Yang, Shang-Dong,Yang, Bin. "Tf2O/DMSO-Promoted P-O and P-S Bond Formation: A Scalable Synthesis of Multifarious Organophosphinates and Thiophosphates". supporting information. p. 1541 - 1547. Retrieved 2021/04/05.
• 2、 Cheng, Feixiang,Liu, Jianjun,Liu, Teng,Yu, Rong,Zhang, Yanqiong. "An Alternative Metal-Free Aerobic Oxidative Cross-Dehydrogenative Coupling of Sulfonyl Hydrazides with Secondary Phosphine Oxides". . p. 253 - 262. Retrieved 2019/12/28.