beta-Mangostin

Base Information

Chemical Name:beta-Mangostin
CAS No.:20931-37-7
Molecular Formula:C25H28O6
Molecular Weight:424.494
Hs Code.:2932999099
DSSTox Substance ID:DTXSID40420546
Nikkaji Number:J15.918B
Wikidata:Q72488190
Metabolomics Workbench ID:47408
ChEMBL ID:CHEMBL261706
Mol file:20931-37-7.mol

Synonyms:beta-mangostin

Suppliers and Price of beta-Mangostin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
β-Mangostin
1mg
$ 250.00

Labseeker
MANGOSTIN,BETA 98
50mg
$ 1046.00

Crysdot
beta-Mangostin 98+%
5mg
$ 147.00

Cayman Chemical
β-Mangostin ≥95%
10mg
$ 1194.00

Cayman Chemical
β-Mangostin ≥95%
5mg
$ 796.00

Cayman Chemical
β-Mangostin ≥95%
1mg
$ 199.00

AvaChem
Beta-Mangostin
5mg
$ 155.00

Arctom
1,6-Dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
10mg
$ 886.36

Arctom
Beta-mangostin ≥98%
10mg
$ 298.00

Arctom
beta-Mangostin ≥98%
5mg
$ 416.00

Total 43 raw suppliers

Chemical Property of beta-Mangostin

Chemical Property:

Appearance/Colour:faintly yellow powder
Vapor Pressure:8.64E-16mmHg at 25°C
Melting Point:175-176 °C
Refractive Index:1.597
Boiling Point:616.5 °C at 760 mmHg
PKA:7.05±0.20(Predicted)
Flash Point:208.3 °C
PSA：89.13000
Density:1.213 g/cm³
LogP:5.39200
Storage Temp.:2-8°C
XLogP3:6.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:424.18858861
Heavy Atom Count:31
Complexity:692

Purity/Quality:

≥98% ^*data from raw suppliers

β-Mangostin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CCC1=C(C=C2C(=C1O)C(=O)C3=C(O2)C=C(C(=C3CC=C(C)C)OC)O)OC)C
Description β-Mangostin is a xanthone originally isolated from G. mangostana with diverse biological activites. It inhibits growth of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA; MICs = 6.25-12.5 and 6.25-25 μg/ml, respectively), P. falciparum (IC50 = 3 μg/ml), and M. tuberculosis (MIC = 6.25 μg/ml). β-Mangostin inhibits fatty acid synthase (FASN) with an IC50 value of 24.83 μM. It induces cell cycle arrest at the G2/M phase and intrinsic and mitochondrial apoptosis in MCF-7 breast cancer cells. β-Mangostin also inhibits LPS-induced nitric oxide and prostaglandin E2 (PGE2; ) production in RAW264.7 cells and reduces neutrophil infiltration and TNF-α and IL-1β production in a mouse model of carrageenan-induced peritonitis.

Technology Process of beta-Mangostin

There total 14 articles about beta-Mangostin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1607022-18-3
3-(allyloxy)-8-hydroxy-2,6-dimethoxy-1,7-bis(3-methylbut-2-en-1-yl)-9H-xanthene-9-one

: 20931-37-7
β-mangostin

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In methanol; at 20 - 80 ℃; for 5h;
DOI:10.1016/j.bmcl.2014.03.047