Technology Process of (S)-3-(4-(2-bromo-5-fluoropyridin-4-yl)phenyl)-5,5-dimethyl-4-phenyloxazolidin-2-one
There total 3 articles about (S)-3-(4-(2-bromo-5-fluoropyridin-4-yl)phenyl)-5,5-dimethyl-4-phenyloxazolidin-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate;
In
1,4-dioxane; water;
at 100 ℃;
for 1h;
Inert atmosphere;
Sealed tube;
Microwave irradiation;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium phosphate; N,N`-dimethylethylenediamine; copper(l) iodide / 1,4-dioxane / 12 h / 100 °C / Sealed tube; Inert atmosphere
2: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / 1,4-dioxane; water / 1 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
potassium phosphate; copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate; N,N`-dimethylethylenediamine;
In
1,4-dioxane; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium phosphate; N,N`-dimethylethylenediamine; copper(l) iodide / 1,4-dioxane / 12 h / 100 °C / Sealed tube; Inert atmosphere
2: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / 1,4-dioxane; water / 1 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
potassium phosphate; copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate; N,N`-dimethylethylenediamine;
In
1,4-dioxane; water;