2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole

Base Information

Chemical Name:2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole
CAS No.:1393843-03-2
Molecular Formula:C₂₃H₂₀ClFN₄O₂
Molecular Weight:438.889
Hs Code.:

Synonyms:2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole

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Chemical Property of 2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole

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Technology Process of 2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole

There total 2 articles about 2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1393843-91-8
2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxylic acid

: 35613-84-4
(Z)-N'-hydroxyisobutyrimidamide

: 1393843-03-2
2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole

Guidance literature:: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield:

: 1393843-93-0
ethyl 2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxylate

: 1393843-03-2
2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-7-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,4-dihydro chromeno[3,4-d]imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 24 h / 10 - 15 °C

2: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide / N,N-dimethyl-formamide / 80 °C

With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide;