tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate

Base Information

Chemical Name:tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate
CAS No.:912971-54-1
Molecular Formula:C₂₉H₃₄N₂O₃
Molecular Weight:458.601
Hs Code.:

Synonyms:tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate

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Chemical Property of tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate

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Technology Process of tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate

There total 1 articles about tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 912971-33-6
2-(2-methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

: 912971-53-0
tert-butyl 10-(trifluoromethylsulfonyloxy)-7-azaspiro[4.5]dec-9-ene-7-carboxylate

: 912971-54-1
tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate

Guidance literature:: With caesium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 100 ℃;

Reference yield:

: 912971-54-1
tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate

: C₂₄H₂₆N₂O

Guidance literature:: tert-butyl 10-(2-(2-methoxyphenyl)-1H-indol-5-yl)-7-azaspiro[4.5]dec-9-ene-7-carboxylate; With trifluoroacetic acid; In 1,1-dichloroethane; at 20 ℃; for 1h;

With ammonia; In methanol; dichloromethane; water;