2-[3-(4-fluorophenyl)-5-phenylisoxazol-4-yl]malonic acid dimethyl ester

Base Information

Chemical Name:2-[3-(4-fluorophenyl)-5-phenylisoxazol-4-yl]malonic acid dimethyl ester
CAS No.:1198577-90-0
Molecular Formula:C₂₀H₁₆FNO₅
Molecular Weight:369.349
Hs Code.:

Synonyms:2-[3-(4-fluorophenyl)-5-phenylisoxazol-4-yl]malonic acid dimethyl ester

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Chemical Property of 2-[3-(4-fluorophenyl)-5-phenylisoxazol-4-yl]malonic acid dimethyl ester

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Technology Process of 2-[3-(4-fluorophenyl)-5-phenylisoxazol-4-yl]malonic acid dimethyl ester

There total 1 articles about 2-[3-(4-fluorophenyl)-5-phenylisoxazol-4-yl]malonic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 42202-95-9
4-fluoro-N-hydroxybenzimidoyl chloride

: 170751-24-3
dimethyl 2-phenyl-cycloprop-2-ene-1,1-dicarboxylic ester

: 1198577-90-0
2-[3-(4-fluorophenyl)-5-phenylisoxazol-4-yl]malonic acid dimethyl ester

Guidance literature:: With 1H-imidazole; In dichloromethane; at 20 ℃; for 55h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2009.09.034