ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate

Base Information

Chemical Name:ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate
CAS No.:742100-44-3
Molecular Formula:C₁₆H₂₀BrNO₃
Molecular Weight:354.244
Hs Code.:

Synonyms:ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate

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Chemical Property of ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate

Chemical Property:

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Technology Process of ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate

There total 1 articles about ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 742101-12-8
ethyl (2E)-3-[5-bromo-2-[3-(tetrahydro-2H-pyran-2-yloxy)pyrrolidin-1-yl]phenyl]-2-methylacrylate

: 742100-44-3
ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate

Guidance literature:: With hydrogenchloride; methanol; water; for 2h;

Reference yield:

: 742100-44-3
ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate

: 742100-45-4
ethyl (2E)-3-[5-bromo-2-(3-oxopyrrolidin-1-yl)phenyl]-2-methylacrylate

Guidance literature:: ethyl (2E)-3-[5-bromo-2-(3-hydroxypyrrolidin-1-yl)phenyl]-2-methylacrylate; With oxalyl dichloride; In dichloromethane; dimethyl sulfoxide; at -78 ℃; for 0.5h;

With triethylamine; In dichloromethane; dimethyl sulfoxide; for 2h;

for 2h;