N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

Base Information

• Chemical Name: N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
• CAS No.: 98911-14-9
• Molecular Formula: C₂₂H₂₇NO₁₁
• Molecular Weight: 481.456
• Mol file: 98911-14-9.mol

Synonyms:N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

Chemical Property of N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

There total 6 articles about N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

acetic anhydride (108-24-7) + Acetic acid (2R,3R,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-(N-phenyl-aminooxy)-tetrahydro-pyran-4-yl ester (98911-26-3) → N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside (98911-14-9)

Guidance literature:

In pyridine;

Reference yield: 59.0%

3,4,6-tri-O-acetyl-1,2-O-<1-(N-acetylanilino-oxy)ethylidene>-α-D-glucopyranose (98911-10-5) → N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside (98911-14-9)

Guidance literature:

2,6-lutidinium perchlorate; In various solvent(s); for 12h; Heating;

Reference yield: 32.0%

N-Phenylacetohydroxamic acid (1795-83-1) + 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide (572-09-8) → N-phenylacetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside (98911-14-9)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 25 ℃; for 1h;

DOI:10.1021/jo202123s

upstream raw materials:

acetic anhydride

1-(N-arylamino)oxy-1-deoxy-β-D-glucopyranose

Acetic acid (2R,3R,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-(N-phenyl-aminooxy)-tetrahydro-pyran-4-yl ester

3,4,6-tri-O-acetyl-1,2-O-<1-(N-acetylanilino-oxy)ethylidene>-α-D-glucopyranose

Downstream raw materials:

1-(N-arylamino)oxy-1-deoxy-β-D-glucopyranose

2,3,4,6-tetra-O-acetyl-β-D-glucopyranose

Acetanilid

N-phenylacetohydroxamic acid β-D-glucopyranoside