3-Phenyl-1-cyclooctene

Base Information

• Chemical Name: 3-Phenyl-1-cyclooctene
• CAS No.: 7287-13-0
• Molecular Formula: C₁₄H₁₈
• Molecular Weight: 186.297
• European Community (EC) Number: 660-104-2
• Nikkaji Number: J1.036.041B,J801.700J
• Mol file: 7287-13-0.mol

Synonyms:3-phenyl-1-cyclooctene;3-phenylcyclooctene;(1Z)-3-phenyl-cyclooctene;(Z)-3-Phenyl-1-cyclooctene;AKOS024324821;7287-13-0

Chemical Property of 3-Phenyl-1-cyclooctene

Chemical Property:

• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 186.140850574
• Heavy Atom Count: 14
• Complexity: 175

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC=CC(CC1)C2=CC=CC=C2
• Isomeric SMILES: C1CC/C=C\C(CC1)C2=CC=CC=C2

Technology Process of 3-Phenyl-1-cyclooctene

There total 11 articles about 3-Phenyl-1-cyclooctene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

cis-Cyclooctene (931-88-4,931-87-3,25267-51-0) + iodobenzene (591-50-4) → (Z)-3-phenylcyclooct-1-ene (7287-13-0)

Guidance literature:

With tetrabutyl-ammonium chloride; cesium acetate; palladium diacetate; In N,N-dimethyl-formamide; at 25 ℃; for 48h;

DOI:10.1016/S0040-4039(00)82478-8

Reference yield: 81.0%

(Z)-3-bromocyclooct-1-ene (7422-06-2) + phenylmagnesium bromide → (Z)-3-phenylcyclooct-1-ene (7287-13-0)

Guidance literature:

(Z)-3-bromocyclooct-1-ene; [Fe(C₂H₄)4][Li(tmeda)]2; In tetrahydrofuran; at -20 ℃;

phenylmagnesium bromide; In tetrahydrofuran; diethyl ether; at -20 ℃; Further stages.;

DOI:10.1021/ja801466t

Reference yield: 77.0%

2-(trimethylsilyl)phenyl trifluoromethanesulfonate (88284-48-4) + 1,2-cyclooctene (931-88-4,22770-27-0,3958-30-3,25267-51-0) → 3-phenylcyclooctene (7287-13-0)

Guidance literature:

With cesium fluoride; In acetonitrile; at 25 ℃; for 12h;

DOI:10.1016/j.tetlet.2013.08.049

upstream raw materials:

cis-Cyclooctene

iodobenzene

phenylazo phenyl sulfone

(Z)-3-bromocyclooct-1-ene