Technology Process of (2R,3R,4R,5R,6R)-3-(benzyloxy)-5-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-2,4-dimethyl-6-([(4-methylphenyl)sulfonyl]oxymethyl)octyl pivalate
There total 10 articles about (2R,3R,4R,5R,6R)-3-(benzyloxy)-5-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-2,4-dimethyl-6-([(4-methylphenyl)sulfonyl]oxymethyl)octyl pivalate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C
2: pyridinium p-toluenesulfonate / dichloromethane / 12 h / 0 - 20 °C
3: triethylamine / dichloromethane / 12 h / 0 - 20 °C
4: toluene-4-sulfonic acid / methanol / 10 h / 0 - 20 °C
5: di(n-butyl)tin oxide; triethylamine / dichloromethane / 10 h / 0 - 20 °C
6: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 - 20 °C
With
2,6-dimethylpyridine; lithium aluminium tetrahydride; pyridinium p-toluenesulfonate; di(n-butyl)tin oxide; toluene-4-sulfonic acid; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/j.tetlet.2011.05.151
- Guidance literature:
-
Multi-step reaction with 4 steps
1: triethylamine / dichloromethane / 12 h / 0 - 20 °C
2: toluene-4-sulfonic acid / methanol / 10 h / 0 - 20 °C
3: di(n-butyl)tin oxide; triethylamine / dichloromethane / 10 h / 0 - 20 °C
4: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 - 20 °C
With
2,6-dimethylpyridine; di(n-butyl)tin oxide; toluene-4-sulfonic acid; triethylamine;
In
methanol; dichloromethane;
DOI:10.1016/j.tetlet.2011.05.151
