3'-azido-3'-deoxy-5'-O-tosyl-3-N-1-[5-(2,2,2-trifluoroacetylamino)-pentyl]thymidine

Base Information

Chemical Name:3'-azido-3'-deoxy-5'-O-tosyl-3-N-1-[5-(2,2,2-trifluoroacetylamino)-pentyl]thymidine
CAS No.:1219019-93-8
Molecular Formula:C₂₄H₂₉F₃N₆O₇S
Molecular Weight:602.591
Hs Code.:

Synonyms:3'-azido-3'-deoxy-5'-O-tosyl-3-N-1-[5-(2,2,2-trifluoroacetylamino)-pentyl]thymidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3'-azido-3'-deoxy-5'-O-tosyl-3-N-1-[5-(2,2,2-trifluoroacetylamino)-pentyl]thymidine

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Technology Process of 3'-azido-3'-deoxy-5'-O-tosyl-3-N-1-[5-(2,2,2-trifluoroacetylamino)-pentyl]thymidine

There total 1 articles about 3'-azido-3'-deoxy-5'-O-tosyl-3-N-1-[5-(2,2,2-trifluoroacetylamino)-pentyl]thymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 98-59-9
p-toluenesulfonyl chloride

: 174571-55-2
3'-azido-3'-deoxy-N³-{1-[5-(2,2,2-trifluoroacetylamino)pentyl]}thymidine

: 1219019-93-8
3'-azido-3'-deoxy-5'-O-tosyl-3-N-1-[5-(2,2,2-trifluoroacetylamino)-pentyl]thymidine

Guidance literature:: 3'-azido-3'-deoxy-N³-{1-[5-(2,2,2-trifluoroacetylamino)pentyl]}thymidine; With dmap; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

p-toluenesulfonyl chloride; Inert atmosphere;
DOI:10.1016/j.bmcl.2009.12.053