N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine

Base Information

• Chemical Name: N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine
• CAS No.: 1069127-54-3
• Molecular Formula: C₂₅H₃₄N₄O₇S
• Molecular Weight: 534.634
• Mol file: 1069127-54-3.mol

Synonyms:N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine

Chemical Property of N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine

There total 1 articles about N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

thymidyl acetic acid (20924-05-4) + N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-ethylenediamine (1069127-53-2) → N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine (1069127-54-3)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;

DOI:10.1080/00397910802219122

Reference yield: 87.0%

N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine (1069127-54-3) → N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-carboxymethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine (1069127-55-4)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; for 0.333333h;

DOI:10.1080/00397910802219122

upstream raw materials:

thymidyl acetic acid

N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-methoxycarbonylmethyl-ethylenediamine

Downstream raw materials:

N-tert-butoxycarbonyl-1-(benzylthiomethyl)-N'-carboxymethyl-N'-[(thymin-1-yl)acetyl]-ethylenediamine