5-Isopropyl-3-phenylimidazolidine-2,4-dione

Base Information

Chemical Name:5-Isopropyl-3-phenylimidazolidine-2,4-dione
CAS No.:103774-42-1
Molecular Formula:C₁₂H₁₄N₂O₂
Molecular Weight:218.255
Hs Code.:
DSSTox Substance ID:DTXSID101230887
Nikkaji Number:J731.583J

Synonyms:5-Isopropyl-3-phenylimidazolidine-2,4-dione;103774-42-1;TimTec1_003678;Oprea1_111768;3-Phenyl-5-isopropylhydantoin;SCHEMBL13879469;DTXSID101230887;HMS1544H04;AKOS001468062;CS-0339716;5-(1-Methylethyl)-3-phenyl-2,4-imidazolidinedione;BRD-A51778860-001-01-3;Z223139458

Suppliers and Price of 5-Isopropyl-3-phenylimidazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-Isopropyl-3-phenylimidazolidine-2,4-dione

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:295

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C1C(=O)N(C(=O)N1)C2=CC=CC=C2

Technology Process of 5-Isopropyl-3-phenylimidazolidine-2,4-dione

There total 11 articles about 5-Isopropyl-3-phenylimidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1207610-46-5
phenylcarbamoyl-valine methylamide

: 103774-42-1
5-isopropyl-3-phenylimidazolidine-2,4-dione

Guidance literature:: With hydrogenchloride; acetic acid; at 70 ℃; for 18h;
DOI:10.1021/tx900278p

Reference yield:

: 516-06-3,25609-85-2,7004-03-7,921-10-8
D,L-valine

: 103774-42-1
5-isopropyl-3-phenylimidazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: alkali / 0 °C

2: hydrochloric acid

With hydrogenchloride;

Reference yield:

: 103-71-9
phenyl isocyanate

: 103774-42-1
5-isopropyl-3-phenylimidazolidine-2,4-dione

Guidance literature:: Boc-Val-Merrifield resin; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

phenyl isocyanate; In tetrahydrofuran; at 60 ℃; for 0.166667h; microwave irradiation;

With triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; at 110 ℃; for 0.25h; Further stages.; microwave irradiation;
DOI:10.1016/j.tetlet.2007.05.084