benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate

Base Information

Chemical Name:benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate
CAS No.:1100750-79-5
Molecular Formula:C₂₄H₂₅FN₄O₅
Molecular Weight:477.413
Hs Code.:

Synonyms:benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate

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Chemical Property of benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate

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Technology Process of benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate

There total 1 articles about benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1100750-74-0
methyl 2-(2-(benzyloxycarbonylamino)-(1,3-d6-propan)-2-yl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidine-4-carboxylate

: 140-75-0
para-fluorobenzylamine

: 1100750-79-5,1189916-86-6
benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate

Guidance literature:: With triethylamine; In ethanol; at 0 - 72 ℃; for 2h;

Reference yield: 42.0%

: 1100750-79-5,1189916-86-6
benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate

: 1100750-80-8,1189508-85-7
2-(2-amino-(1,3-d6-propan)-2-yl)-N-4-fluorobenzyl-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidine-4-carboxamide

Guidance literature:: benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-(methyl-d3)-6-oxo-1,6-dihydropyrimidin-2-yl)-(1,3-d6-propan)-2-ylcarbamate; With hydrogen; palladium on activated carbon; In ethanol; for 4h; under 2585.81 Torr;

With sodium hydroxide; In dichloromethane; water;