Technology Process of 2-methoxy-5-(3,4,5-trimethoxyphenyl)naphthalen-1-ol
There total 4 articles about 2-methoxy-5-(3,4,5-trimethoxyphenyl)naphthalen-1-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); potassium hydroxide; tert-butyl XPhos;
In
1,4-dioxane; water;
at 90 ℃;
for 1h;
Sealed vessel;
DOI:10.1016/j.ejmech.2012.03.001
- Guidance literature:
-
Multi-step reaction with 4 steps
1: magnesium sulfate; toluene-4-sulfonic acid / ethanol / 2 h / Reflux
2: tris-(dibenzylideneacetone)dipalladium(0); lithium tert-butoxide; XPhos / 1,4-dioxane; dichloromethane / 5 h / 90 °C / Sealed vessel
3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1 h / 20 °C
4: tris-(dibenzylideneacetone)dipalladium(0); potassium hydroxide; tert-butyl XPhos / 1,4-dioxane; water / 1 h / 90 °C / Sealed vessel
With
tris-(dibenzylideneacetone)dipalladium(0); magnesium sulfate; toluene-4-sulfonic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; potassium hydroxide; lithium tert-butoxide; tert-butyl XPhos; XPhos;
In
1,4-dioxane; ethanol; dichloromethane; water;
DOI:10.1016/j.ejmech.2012.03.001
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tris-(dibenzylideneacetone)dipalladium(0); lithium tert-butoxide; XPhos / 1,4-dioxane; dichloromethane / 5 h / 90 °C / Sealed vessel
2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1 h / 20 °C
3: tris-(dibenzylideneacetone)dipalladium(0); potassium hydroxide; tert-butyl XPhos / 1,4-dioxane; water / 1 h / 90 °C / Sealed vessel
With
tris-(dibenzylideneacetone)dipalladium(0); 2,3-dicyano-5,6-dichloro-p-benzoquinone; potassium hydroxide; lithium tert-butoxide; tert-butyl XPhos; XPhos;
In
1,4-dioxane; dichloromethane; water;
DOI:10.1016/j.ejmech.2012.03.001
