Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

Base Information

Chemical Name:Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn
CAS No.:266318-86-9
Molecular Formula:C₄₆H₇₈N₆O₉
Molecular Weight:859.16
Hs Code.:

Boc-(R)-β<sup>3</sup>-HVal-(S)-β<sup>3</sup>-HAla-(S)-β<sup>3</sup>-HLeu-(R)-β<sup>3</sup>-HVal-(S)-β<sup>3</sup>-HAla-(S)-β<sup>3</sup>-HLeu-OBn

Synonyms:Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

Suppliers and Price of Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

There total 3 articles about Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 181075-71-8
Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OH

: H-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

: 266318-86-9
Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In chloroform; N,N-dimethyl-formamide; at 20 ℃; for 21h;
DOI:10.1002/(SICI)1522-2675(20000119)83:1<34::AID-HLCA34>3.0.CO;2-B

Reference yield:

: 210345-74-7
Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

: 266318-86-9
Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / H₂ / Pd/C / methanol / 19 h

2: 25 percent / NMM; HOBt; EDC / CHCl₃; dimethylformamide / 21 h / 20 °C

With 4-methyl-morpholine; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In methanol; chloroform; N,N-dimethyl-formamide; 1: Hydrogenolysis / 2: Condensation;
DOI:10.1002/(SICI)1522-2675(20000119)83:1<34::AID-HLCA34>3.0.CO;2-B

Reference yield:

: 181075-63-8
Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OMe

: 266318-86-9
Boc-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-(R)-β³-HVal-(S)-β³-HAla-(S)-β³-HLeu-OBn

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / NaOH / methanol; tetrahydrofuran / 11 h

2: 25 percent / NMM; HOBt; EDC / CHCl₃; dimethylformamide / 21 h / 20 °C

With 4-methyl-morpholine; sodium hydroxide; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In tetrahydrofuran; methanol; chloroform; N,N-dimethyl-formamide; 1: Hydrolysis / 2: Condensation;
DOI:10.1002/(SICI)1522-2675(20000119)83:1<34::AID-HLCA34>3.0.CO;2-B