Cyclopropylacetonitrile

Base Information

• Chemical Name: Cyclopropylacetonitrile
• CAS No.: 6542-60-5
• Molecular Formula: C5H7N
• Molecular Weight: 81.1173
• Hs Code.: 29269090
• Mol file: 6542-60-5.mol

Synonyms:(Cyanomethyl)cyclopropane;2-Cyclopropylacetonitrile;Cyclopropylacetonitrile;Cyclopropylcarbinylcyanide;Cyclopropylmethyl cyanide;

Chemical Property of Cyclopropylacetonitrile

Chemical Property:

• Vapor Pressure: 2.46mmHg at 25°C
• Refractive Index: n20/D 1.4235(lit.)
• Boiling Point: 159.8 °C at 760 mmHg
• Flash Point: 57.4 °C
• PSA: 23.79000
• Density: 0.963 g/cm³
• LogP: 1.31008
• Storage Temp.: 2-8°C
• Water Solubility.: Miscible with water, methylene chloride and alcohols.

Purity/Quality:

98% ^*data from raw suppliers

Cyclopropaneacetonitrile 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 10-68-23/24/25
• Safety Statements: 26-36/37/39-45-36/37-23

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Cyclopropylacetonitrile is used in the preparation of cyclopropyl-2 acetophenone and cyclopropylacetyl chloride. It acts as an organic intermediate in organic synthesis. It is also employed in the preparation of agrochemicals, pharmaceuticals and dyestuff fields.

Technology Process of Cyclopropylacetonitrile

There total 8 articles about Cyclopropylacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

potassium cyanide + cyclopropylcarbinyl bromide (7051-34-5) → 2-cyclopropylacetonitrile (6542-60-5)

Guidance literature:

In dimethyl sulfoxide; at 110 ℃; for 5h; Inert atmosphere;

Reference yield: 76.7%

cyclopropylacetaldehyde oxime (530133-49-4) → 2-cyclopropylacetonitrile (6542-60-5)

Guidance literature:

With acetic anhydride; In ethyl acetate; at 25 ℃; for 3.5h; Heating / reflux;

Reference yield: 75.0%

sodium cyanide (143-33-9,25596-52-5) + cyclopropylcarbinyl bromide (7051-34-5) → 2-cyclopropylacetonitrile (6542-60-5)

Guidance literature:

phase transfer;

DOI:10.1039/c39820001037

upstream raw materials:

potassium cyanide

cyclopropylcarbinyl bromide

Cyclopropylmethanol

sodium cyanide

Downstream raw materials:

cyclopropylacetic acid

2-(cyclopropyl)ethylamine

1,2-dicyclopropylethanone

2-cyclopropyl-1-phenylethanone