4-(N,N-dimethylamino)-1,8-naphthalic anhydride

Base Information

• Chemical Name: 4-(N,N-dimethylamino)-1,8-naphthalic anhydride
• CAS No.: 77976-79-5
• Molecular Formula: C₁₄H₁₁NO₃
• Molecular Weight: 241.246
• Mol file: 77976-79-5.mol

Synonyms:4-(N,N-dimethylamino)-1,8-naphthalic anhydride

Chemical Property of 4-(N,N-dimethylamino)-1,8-naphthalic anhydride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(N,N-dimethylamino)-1,8-naphthalic anhydride

There total 3 articles about 4-(N,N-dimethylamino)-1,8-naphthalic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.7%

4-bromo-1,8-naphthalenedicarboxylic anhydride (81-86-7) + 3-dimethylaminopropiononitrile (1738-25-6) → 4-(N,N-dimethylamino)-1,8-naphthalic anhydride (77976-79-5) + dimethylaminopropionitrile hydrobromide (253875-98-8) + acrylonitrile (107-13-1,25014-41-9)

Guidance literature:

In i-Amyl alcohol; at 132 ℃; for 12h;

Reference yield: 95.0%

4-bromo-1,8-naphthalenedicarboxylic anhydride (81-86-7) + 3-dimethylaminopropiononitrile (1738-25-6) → 4-(N,N-dimethylamino)-1,8-naphthalic anhydride (77976-79-5) + acrylonitrile (107-13-1,25014-41-9)

Guidance literature:

In i-Amyl alcohol; at 130 ℃; for 15h; Rate constant; other solvent; other temperature;

Reference yield: 20.8%

4-bromo-1,8-naphthalenedicarboxylic anhydride (81-86-7) + 3-dimethylaminopropiononitrile (1738-25-6) → 1,8-Naphthalimide (81-83-4) + 4-(N,N-dimethylamino)-1,8-naphthalic anhydride (77976-79-5) + 3-(6-Dimethylamino-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propionitrile (83927-02-0) + 4-N,N-dimethylaminonaphthalimide (82616-18-0)

Guidance literature:

With methanol; at 130 ℃;

upstream raw materials:

4-bromo-1,8-naphthalenedicarboxylic anhydride

3-dimethylaminopropiononitrile

Downstream raw materials:

2-[6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl]ethyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate

2-{2-[6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl]ethoxy}ethyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-{6-[6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl]hexyl}acetamide

2-(4-dimethylamino-1,8-naphthalimido)ethyl isocyanide