[Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester

Base Information

Chemical Name:[Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester
CAS No.:135473-49-3
Molecular Formula:C₂₀H₂₇FNO₃P
Molecular Weight:379.411
Hs Code.:

Synonyms:[Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester

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Chemical Property of [Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester

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Technology Process of [Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester

There total 2 articles about [Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.4%

: 1809-20-7
diisopropyl hydrogenphosphonate

: 67907-60-2
N-(4-fluorophenylmethylene)-benzylamine

: 135473-49-3
[Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester

Guidance literature:: With boron trifluoride diethyl etherate; In diethyl ether; at 20 ℃; for 14h;

Reference yield:

: 100-46-9
benzylamine

: 135473-49-3
[Benzylamino-(4-fluoro-phenyl)-methyl]-phosphonic acid diisopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 88.6 percent / Na₂SO₄ / CH₂Cl₂ / 1 h / Ambient temperature

2: 47.4 percent / BF₃*Et₂O / diethyl ether / 14 h / 20 °C

With boron trifluoride diethyl etherate; sodium sulfate; In diethyl ether; dichloromethane;