6-hydroxycaproic acid 4-chlorophenyl ester

Base Information

• Chemical Name: 6-hydroxycaproic acid 4-chlorophenyl ester
• CAS No.: 1228686-31-4
• Molecular Formula: C₁₂H₁₅ClO₃
• Molecular Weight: 242.702
• Mol file: 1228686-31-4.mol

Synonyms:6-hydroxycaproic acid 4-chlorophenyl ester

Chemical Property of 6-hydroxycaproic acid 4-chlorophenyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 6-hydroxycaproic acid 4-chlorophenyl ester

There total 1 articles about 6-hydroxycaproic acid 4-chlorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

6-Hydroxyhexanoic acid (1191-25-9) + 4-chloro-phenol (106-48-9,82344-39-6) → 6-hydroxycaproic acid 4-chlorophenyl ester (1228686-31-4)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo1004636

Reference yield: 75.0%

6-hydroxycaproic acid 4-chlorophenyl ester (1228686-31-4) → hexahydro-2H-oxepin-2-one (502-44-3,24980-41-4,80137-66-2)

Guidance literature:

With tetrabutylammonium tricarbonylnitrosylferrate; In tetrahydrofuran; at 80 ℃; for 24h; Molecular sieve;

DOI:10.1021/jo1004636

upstream raw materials:

6-Hydroxyhexanoic acid

4-chloro-phenol

Downstream raw materials:

hexahydro-2H-oxepin-2-one

Refernces