(2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester

Base Information

Chemical Name:(2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester
CAS No.:401606-63-1
Molecular Formula:C₃₉H₅₂N₂O₁₁
Molecular Weight:724.849
Hs Code.:

(2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester

Synonyms:(2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester

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Chemical Property of (2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester

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Technology Process of (2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester

There total 2 articles about (2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 621-84-1
O-benzyl carbamate

: 401606-62-0
(E)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-acrylic acid ethyl ester

: C₃₉H₅₂N₂O₁₁

: 1013210-02-0
C₃₉H₅₂N₂O₁₁

: 401606-74-4
C₃₉H₅₂N₂O₁₁

: 401606-63-1
(2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester

Guidance literature:: With sodium hydroxide; tert-butylhypochlorite; K2; In propan-1-ol; water;
DOI:10.1021/ja710363p

Reference yield:

: 621-84-1
O-benzyl carbamate

: 401606-62-0
(E)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-acrylic acid ethyl ester

: 401606-63-1
(2S,3R)-3-[4-Benzyloxy-3-((1R,2R)-2-tert-butoxycarbonylamino-1-ethyl-3-methoxymethoxy-1-methyl-propoxy)-phenyl]-2-benzyloxycarbonylamino-3-hydroxy-propionic acid ethyl ester

Guidance literature:: With sodium hydroxide; hydroquinidine anthraquinone-1,4-diyl diether; tert-butylhypochlorite; K2; In propan-1-ol; at 20 ℃; for 1h; Product distribution;
DOI:10.1021/ja017277z