N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

Base Information

Chemical Name:N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide
CAS No.:1612143-74-4
Molecular Formula:C₂₉H₃₄N₂O₂
Molecular Weight:442.601
Hs Code.:

Synonyms:N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

Suppliers and Price of N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

There total 3 articles about N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 1313759-98-6
N-(cis-3-hydroxy-3-(2-oxoethyl)cyclobutyl)-2-naphthamide

: 1612143-73-3
(1R,2S)-2-phenyl-N-propylcyclopropan-1-amine

: 1612143-74-4
N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1021/jm401798r

Reference yield:

: 95-62-5,155-09-9,3721-26-4,3721-28-6,13531-35-6,24873-95-8,69684-88-4,69684-89-5,54-97-7
(1R,2S)-1-amino-2-phenylcyclopropane

: 1612143-74-4
N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

Guidance literature:: Multi-step reaction with 3 steps

1: methanol / 20 °C

2: sodium tetrahydroborate / methanol / 1 h / 20 °C

3: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 4 h / 20 °C

With sodium tetrahydroborate; sodium tris(acetoxy)borohydride; acetic acid; In methanol; dichloromethane;
DOI:10.1021/jm401798r

Reference yield:

: C₁₂H₁₅N

: 1612143-74-4
N-(cis-3-hydroxy-3-(2-(((1R,2S)-2-phenylcyclopropyl)(propyl)amino)ethyl)cyclobutyl)-2-naphthamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 1 h / 20 °C

2: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 4 h / 20 °C

With sodium tetrahydroborate; sodium tris(acetoxy)borohydride; acetic acid; In methanol; dichloromethane;
DOI:10.1021/jm401798r