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2-Aminoethylmethylsulfone hydrochloride

Base Information Edit
  • Chemical Name:2-Aminoethylmethylsulfone hydrochloride
  • CAS No.:104458-24-4
  • Molecular Formula:C3H9NO2S.HCl
  • Molecular Weight:159.637
  • Hs Code.:29211990
  • Mol file:104458-24-4.mol
2-Aminoethylmethylsulfone hydrochloride

Synonyms:Ethanamine,2-(methylsulfonyl)-, hydrochloride (9CI);2-(Methylsulfonyl)ethanaminehydrochloride;2-(Methylsulfonyl)ethylamine hydrochloride;2-Aminoethyl methylsulfone hydrochloride;2-aminoethylmethylsulfone hydrochloride;

Suppliers and Price of 2-Aminoethylmethylsulfone hydrochloride
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 2-(Methylsulfonyl)ethylamineHydrochloride
  • 2.5g
  • $ 95.00
  • TCI Chemical
  • 2-Aminoethyl Methyl Sulfone Hydrochloride >98.0%(N)(T)
  • 5g
  • $ 44.00
  • SynQuest Laboratories
  • 2-Aminoethylmethylsulfone hydrochloride
  • 1 g
  • $ 80.00
  • SynQuest Laboratories
  • 2-Aminoethylmethylsulfone hydrochloride
  • 10 g
  • $ 152.00
  • SynQuest Laboratories
  • 2-Aminoethylmethylsulfone hydrochloride
  • 100 g
  • $ 552.00
  • Crysdot
  • 2-(Methylsulfonyl)ethanaminehydrochloride 98%
  • 500g
  • $ 592.00
  • Crysdot
  • 2-(Methylsulfonyl)ethanaminehydrochloride 98%
  • 100g
  • $ 297.00
  • Chemcia Scientific
  • 2-Aminoethylmethylsulphonehydrochloride 95%
  • 50 G
  • $ 345.00
  • ChemBridge Corporation
  • [2-(methylsulfonyl)ethyl]aminehydrochloride 95%
  • 1 g
  • $ 46.00
  • Biosynth Carbosynth
  • 2-Aminoethylmethylsulfone Hydrochloride
  • 50 g
  • $ 450.00
Total 204 raw suppliers
Chemical Property of 2-Aminoethylmethylsulfone hydrochloride Edit
Chemical Property:
  • Appearance/Colour:power 
  • Vapor Pressure:0.000163mmHg at 25°C 
  • Melting Point:168.0 to 172.0 °C 
  • Boiling Point:325.8 °C at 760 mmHg 
  • Flash Point:150.8 °C 
  • PSA:68.54000 
  • LogP:1.57280 
  • Storage Temp.:Room temperature. 
  • Solubility.:DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated) 
Purity/Quality:

99% *data from raw suppliers

2-(Methylsulfonyl)ethylamineHydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Description Lapatinib is a new drug targeted for the treatment of breast cancer developed by GlaxoSmithKline, which was approved for marketing by the US Food and Drug Administration on March 13, 2007. The currently approved indications are advanced mastocarcinoma treated with lapatinib and capecitabine or metastatic breast cancer, and breast cancer patients must be treated first in other first-class drugs. Its trade name is Tykerb in the United States. On December 14, 2007, the European Medicines Agency (EMEA) approved for marketing of lapatinib in Europe, and the trade name is Tyverb. Breast cancer molecular targeted therapy is the treatment for oncogene related with occurrence and development of breast cancer, and for its related expression product. Molecular targeted drugs control the changes of gene expression in the cell through blocking signal transduction of tumor cell or related cell, thereby inhibiting or killing tumor cells. Lapatinib is a small molecule epidermal growth factor tyrosine kinase inhibitor orally. Clinical trials have shown that lapatinib has a very good clinical effect in patients with HER2 breast cancer who have been resistant to Roche's Herceptin. In vitro, the inhibitory effect of lapatinib on the growth of Her-2 overexpressing breast cancer cell lines was significant. Lapatinib is also highly effective in the Phase I clinical trial of Her-2 overexpression in advanced breast cancer and has no cross-resistance with Herceptin (trastuzumab). Unlike Herceptin (trastuzumab), its structure is small molecules, so it could get through the blood-brain barrier, thereby having a certain therapeutic effect for breast cancer brain metastases.
  • Uses 2-(Methylsulfonyl)ethylamine Hydrochloride is used in the synthetic preparation of potent and selective PI3Kδ inhibitors.
Technology Process of 2-Aminoethylmethylsulfone hydrochloride

There total 6 articles about 2-Aminoethylmethylsulfone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃;
Guidance literature:
With hydrogenchloride; dihydrogen peroxide; In water; at 25 - 30 ℃; pH=3 - 4; Solvent;
Guidance literature:
With hydrogenchloride; water; at 100 ℃; for 10h; Reagent/catalyst; Temperature;
Refernces Edit
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