3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde

Base Information

• Chemical Name: 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde
• CAS No.: 23660-00-6
• Molecular Formula: C₁₇H₂₂O₃
• Molecular Weight: 274.36
• Mol file: 23660-00-6.mol

Synonyms:3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde

Chemical Property of 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde

There total 6 articles about 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

trans-geranyl bromide (6138-90-5) + 2,4-Dihydroxybenzaldehyde (95-01-2) → 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde (23660-00-6)

Guidance literature:

With aluminum oxide; In diethyl ether; at 20 ℃; for 72h; regioselective reaction; Inert atmosphere;

DOI:10.1002/bkcs.10442

Reference yield:

2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4-formyl-3-hydroxyphenyl acetate → 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde (23660-00-6)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 3h;

DOI:10.1016/j.ejmech.2017.09.067

Reference yield:

trans-geranyl bromide (6138-90-5) → 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde (23660-00-6)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium iodide; potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: fuorosil / toluene / 3 h / Reflux

3: sodium hydroxide / tetrahydrofuran; methanol; water / 3 h / 20 °C

With potassium carbonate; potassium iodide; sodium hydroxide; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.ejmech.2017.09.067

upstream raw materials:

trans-geranyl bromide

2,4-Dihydroxybenzaldehyde

Geraniol

acetic acid 4-formyl-3-hydroxyphenyl ester

Downstream raw materials:

mulberrofuran L

5-(7-(3,7-dimethylocta-2,6-dien-1-yl)-6-methoxybenzofuran-2-yl)benzene-1,3-diol

(E)-3-(3,7-dimethylocta-2,6-dienyl)-2-hydroxy-4-methoxybenzaldehyde