1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one

Base Information

• Chemical Name: 1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one
• CAS No.: 330657-31-3
• Molecular Formula: C₂₃H₂₅NO
• Molecular Weight: 331.458
• Mol file: 330657-31-3.mol

Synonyms:1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one

Chemical Property of 1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one

There total 2 articles about 1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-ethyl-4-piperidone (3612-18-8) + 4-methyl-benzaldehyde (104-87-0) → 1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one (330657-31-3)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 20 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2010.07.053

Reference yield: 71.0%

→ 1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one (330657-31-3)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 0 ℃; for 6h; Reflux;

Reference yield: 85.0%

1-ethyl-3,5-bis(4-methylbenzylidene)piperid in-4-one (330657-31-3) + thiourea (17356-08-0) → 6-ethyl-8-(4-methylphenylmethylene)-4-(4-methylphenyl)-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidine-2(1H)-thione

Guidance literature:

With potassium hydroxide; In ethanol; water; for 3h; Reflux;

DOI:10.1016/j.ejmech.2010.07.053

upstream raw materials:

N-ethyl-4-piperidone

4-methyl-benzaldehyde