diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate

Base Information

• Chemical Name: diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate
• CAS No.: 1448308-58-4
• Molecular Formula: C₂₉H₂₈N₂O₇
• Molecular Weight: 516.551
• Mol file: 1448308-58-4.mol

Synonyms:diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate

Chemical Property of diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate

There total 3 articles about diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

7-[(3-methyl-2-butenyl)oxy]-3-{1-[(E)-2-phenylhydrazono]ethyl}-2H-chromen-2-one (1448308-36-8) + acetylenedicarboxylic acid diethyl ester (762-21-0) → diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate (1448308-58-4)

Guidance literature:

at 130 ℃; for 10h;

DOI:10.1016/j.ejmech.2013.03.042

Reference yield:

2-hydroxy-4-(3-methylbut-2-enyloxy)benzaldehyde (61235-37-8) → diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate (1448308-58-4)

Guidance literature:

Multi-step reaction with 3 steps

1: piperidine / dichloromethane; acetonitrile / 4 h / 20 °C

2: acetic acid / water; methanol / 0.5 h / 60 °C

3: 10 h / 130 °C

With piperidine; acetic acid; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1016/j.ejmech.2013.03.042

Reference yield:

7-(3-methylbut-2-enyloxy)-3-acetyl-2H-chromen-2-one (1205132-12-2) → diethyl 3-[7-(3-methylbut-2-enyloxy)-2-oxo-2H-chromene-3-yl]-1-phenyl-1H-pyrazole-4,5-dicarboxylate (1448308-58-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / water; methanol / 0.5 h / 60 °C

2: 10 h / 130 °C

With acetic acid; In methanol; water;

DOI:10.1016/j.ejmech.2013.03.042

upstream raw materials:

7-[(3-methyl-2-butenyl)oxy]-3-{1-[(E)-2-phenylhydrazono]ethyl}-2H-chromen-2-one

acetylenedicarboxylic acid diethyl ester

2-hydroxy-4-(3-methylbut-2-enyloxy)benzaldehyde

7-(3-methylbut-2-enyloxy)-3-acetyl-2H-chromen-2-one