N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole

Base Information

Chemical Name:N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole
CAS No.:1391823-30-5
Molecular Formula:C₁₇H₂₀N₄O₂S₂
Molecular Weight:376.503
Hs Code.:

Synonyms:N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole

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Technology Process of N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole

There total 2 articles about N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1268706-05-3
N-{3-(2-methylbenzylidencarbamyl)-propyl}-2-aminothiazole

: 68-11-1
mercaptoacetic acid

: 1391823-30-5
N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole

Guidance literature:: With zinc(II) chloride; In methanol; at 80 - 90 ℃;
DOI:10.1007/s12039-011-0123-2

Reference yield:

: 1268705-87-8
N-(3-chloropropyl)-2-aminothiazole

: 1391823-30-5
N-3-[(2-(2-methylphenyl)-4-oxo-1,3-thiazolidin-3-yl)carbamyl]propyl-2-aminothiazole

Guidance literature:: Multi-step reaction with 3 steps

1: methanol / 8 h / 20 °C

2: methanol / 20 °C / Heating

3: zinc(II) chloride / methanol / 80 - 90 °C

With zinc(II) chloride; In methanol;
DOI:10.1007/s12039-011-0123-2