dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester

Base Information

• Chemical Name: dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester
• CAS No.: 1026328-87-9
• Molecular Formula: C₉H₈ClIOS₂
• Molecular Weight: 358.651
• Mol file: 1026328-87-9.mol

Synonyms:dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester

Chemical Property of dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester

There total 1 articles about dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-chloro-o-iodoaniline (63069-48-7) + potassium ethyl xanthogenate (140-89-6) → dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester (1026328-87-9)

Guidance literature:

p-chloro-o-iodoaniline; With hydrogenchloride; sodium nitrite; at 0 - 5 ℃; for 0.5h;

potassium ethyl xanthogenate; In water; at 50 - 55 ℃; for 0.5h;

DOI:10.1021/jo9913098

Reference yield:

dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester (1026328-87-9) → 4-chloro-2-iodothiophenol (62835-70-5)

Guidance literature:

With potassium hydroxide; In ethanol; for 10h; Heating;

DOI:10.1021/jo9913098

Reference yield:

dithiocarbonic acid S-(4-chloro-2-iodo-phenyl) ester O-ethyl ester (1026328-87-9) → 6-chloro-2-cyclohexyl-3-methylene-2,3-dihydro-4H-1-benzothiopyran-4-one

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol / 10 h / Heating

2: 77 percent / i-Pr₂NEt; Pd(OAc)2; 1,1'-bis(diphenylphosphino)ferrocene / benzene / 100 °C / 20685.9 Torr

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; potassium hydroxide; N-ethyl-N,N-diisopropylamine; In ethanol; benzene; 1: Hydrolysis / 2: Carbonylation;

DOI:10.1021/jo9913098

upstream raw materials:

p-chloro-o-iodoaniline

potassium ethyl xanthogenate

Downstream raw materials:

4-chloro-2-iodothiophenol