(R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate

Base Information

Chemical Name:(R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate
CAS No.:1351934-97-8
Molecular Formula:C₂₈H₃₁N₃O₇
Molecular Weight:521.57
Hs Code.:

Synonyms:(R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate

Chemical Property:

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Technology Process of (R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate

There total 2 articles about (R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1351934-98-9
(2R)-4-(tetrahydro-2H-pyran-2-yloxycarbamoyl)benzyl 3-(5-(benzyloxy)pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate

: 1351934-97-8
(R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate

Guidance literature:: With Dowex 50wX₈; for 1h; Reflux;

Reference yield:

: 3006-96-0
3-hydroxymethyl-benzoic acid

: 1351934-97-8
(R)-4-(hydroxycarbamoyl)benzyl 3-(5-(benzyloxy)-pyridin-2-yl)-2-(tert-butoxycarbonylamino)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 2 h / 20 °C

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 1 h / 0 - 20 °C

3: Dowex 50wX₈ / 1 h / Reflux

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dicyclohexyl-carbodiimide; In dichloromethane;