6-Hydroxypyridine-3-sulfonic acid

Base Information

• Chemical Name: 6-Hydroxypyridine-3-sulfonic acid
• CAS No.: 6684-46-4
• Molecular Formula: C₅H₅NO₄S
• Molecular Weight: 175.165
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID80376513
• Wikidata: Q72481611
• Mol file: 6684-46-4.mol

Synonyms:6-HYDROXYPYRIDINE-3-SULFONIC ACID;6684-46-4;6-oxo-1H-pyridine-3-sulfonic Acid;6-Hydroxy-3-pyridinesulphonic acid;SCHEMBL2344629;DTXSID80376513;STL490539;AKOS000267483;6-HYDROXYPYRIDINE-3-SULFONICACID;CS-0367398;FT-0645474;A835566

Chemical Property of 6-Hydroxypyridine-3-sulfonic acid

Chemical Property:

• PKA: -5.66±0.20(Predicted)
• PSA: 95.87000
• Density: 1.71g/cm3
• LogP: 1.11470
• Storage Temp.: 2-8°C
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 174.99392881
• Heavy Atom Count: 11
• Complexity: 332

Purity/Quality:

99% ^*data from raw suppliers

6-Hydroxy-3-pyridinesulfonic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=O)NC=C1S(=O)(=O)O

Technology Process of 6-Hydroxypyridine-3-sulfonic acid

There total 1 articles about 6-Hydroxypyridine-3-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-hydroxy-pyridine-3-sulfonic acid (6684-46-4)

Guidance literature:

Diazotization_.Zersetzen der Diazo-Loesung in Schwefelsaeure oder Salzsaeure;

Reference yield:

6-hydroxy-pyridine-3-sulfonic acid (6684-46-4) → 2-chloropyridine-5-sulfonic acid (17624-08-7)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅; POCl₃ / 120 - 130 °C

2: diethyl ether; concentrated aqueous HCl

With hydrogenchloride; diethyl ether; phosphorus pentachloride; trichlorophosphate;

Reference yield:

6-hydroxy-pyridine-3-sulfonic acid (6684-46-4) → 6-chloro-pyridine-3-sulfonic acid amide (40741-46-6)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅; POCl₃ / 120 - 130 °C

2: acetone; 4>2CO₃

With phosphorus pentachloride; ammonium carbonate; acetone; trichlorophosphate;

Downstream raw materials:

6-chloro-pyridine-3-sulfonic acid amide

2-chloropyridine-5-sulfonic acid