tert-butyl (S)-1-hydroxy-3-((S)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

Base Information

Chemical Name:tert-butyl (S)-1-hydroxy-3-((S)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate
CAS No.:942144-43-6
Molecular Formula:C13H25 N O4
Molecular Weight:259.346
Hs Code.:2932999099
Mol file:942144-43-6.mol

Synonyms:tert-butyl (S)-1-hydroxy-3-((S)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

Suppliers and Price of tert-butyl (S)-1-hydroxy-3-((S)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl((S)-1-hydroxy-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl)carbamate 95+%
1g
$ 1265.00

Chemenu
tert-butyl((S)-1-hydroxy-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl)carbamate 95%
1g
$ 1193.00

American Custom Chemicals Corporation
TERT-BUTYL ((S)-1-HYDROXY-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)CARBAMATE 95.00%
5MG
$ 501.79

Total 5 raw suppliers

Chemical Property of tert-butyl (S)-1-hydroxy-3-((S)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

Chemical Property:

PSA：67.79000
LogP:2.07960
Storage Temp.:2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

tert-Butyl((S)-1-hydroxy-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl (S)-1-hydroxy-3-((S)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

There total 10 articles about tert-butyl (S)-1-hydroxy-3-((S)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 942144-34-5
(S)-tert-butyl 2,2-dimethyl-4-(((R)-tetrahydro-2H-pyran-3-yl)methyl)oxazolidine-3-carboxylate

: 24424-99-5
di-tert-butyl dicarbonate

: 942144-43-6,942144-42-5
tert-butyl (S)-1-hydroxy-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

Guidance literature:: (S)-tert-butyl 2,2-dimethyl-4-(((R)-tetrahydro-2H-pyran-3-yl)methyl)oxazolidine-3-carboxylate; With methanol; toluene-4-sulfonic acid; at 20 ℃; for 12h;

di-tert-butyl dicarbonate; With triethylamine; In methanol; for 0.5h;

Reference yield:

: 942144-12-9
tert-butyl (2S,4R)-1-hydroxy-4-(hydroxymethyl)hept-6-en-2-ylcarbamate

: 942144-43-6,942144-42-5
tert-butyl (S)-1-hydroxy-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

Guidance literature:: Multi-step reaction with 6 steps

1.1: toluene-4-sulfonic acid / acetone / 1 h / -20 - 20 °C

2.1: 1H-imidazole; dmap / dichloromethane / 16 h / 20 °C

3.1: dimethylsulfide borane complex / tetrahydrofuran / 5 h / Cooling with ice

3.2: 16 h / 20 °C

4.1: triethylamine / dichloromethane / 1 h / 0 - 20 °C

5.1: tetraethylammonium fluoride / tetrahydrofuran / 16 h / Reflux

6.1: water; acetic acid / 1.5 h / Heating

With 1H-imidazole; dmap; dimethylsulfide borane complex; water; tetraethylammonium fluoride; toluene-4-sulfonic acid; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane; acetone;
DOI:10.1021/ml200137x

Reference yield:

: 942144-13-0
(S)-tert-butyl 4-((R)-2-(hydroxymethyl)pent-4-enyl)-2,2-dimethyloxazolidine-3-carboxylate

: 942144-43-6,942144-42-5
tert-butyl (S)-1-hydroxy-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1H-imidazole; dmap / dichloromethane / 16 h / 20 °C

2.1: dimethylsulfide borane complex / tetrahydrofuran / 5 h / Cooling with ice

2.2: 16 h / 20 °C

3.1: triethylamine / dichloromethane / 1 h / 0 - 20 °C

4.1: tetraethylammonium fluoride / tetrahydrofuran / 16 h / Reflux

5.1: water; acetic acid / 1.5 h / Heating

With 1H-imidazole; dmap; dimethylsulfide borane complex; water; tetraethylammonium fluoride; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ml200137x